Search results for "5]benzoxazepine"

showing 4 items of 4 documents

Synthesis of isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine: two new ring systems of pharmaceutical interest

2015

Abstract Two new ring systems, isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine, were conveniently synthesized through cyclization of suitably substituted isoindole derivatives. Some of the new compounds exhibited antiproliferative activity against a wide range of human tumor cell lines with GI 50 mean values at low micromolar level (3.72–5.13 μM).

Isoindolo[15]benzoxazepineChemistryStereochemistryDrug Discovery3003 Pharmaceutical ScienceOrganic Chemistry5]benzoxazepine4]benzoxazinoneAntiproliferative activityRing (chemistry)Settore CHIM/08 - Chimica FarmaceuticaBiochemistryHuman tumorchemistry.chemical_compoundIsoindolo[14]benzoxazinoneDrug DiscoveryIsoindolo[1Antiproliferative activity; Isoindole; Isoindolo[1; 4]benzoxazinone; Isoindolo[1; 5]benzoxazepine; Biochemistry; Organic Chemistry; Drug Discovery3003 Pharmaceutical ScienceIsoindoleIsoindole
researchProduct

Isoindolo[1,5]benzoxazepines as potential antitumor and/or antiviral agents

2013

Isoindolo[15]benzoxazepines antitumor antiviral agentsSettore CHIM/08 - Chimica Farmaceutica
researchProduct

Synthesis of Azole-Heterocycles as Potential Antitumor and/or Antiviral Agents

2014

NNRTIantitumor agentoxazoleG-quadruplex ligandisoindolo[12-d][15]benzoxazepinetriazolesSettore CHIM/08 - Chimica Farmaceutica
researchProduct

Isoindolo[1,5]benzoxazepine as Potential Antitumor and/or Antiviral Agents

2013

Settore CHIM/08 - Chimica FarmaceuticaIsoindolo[15]benzoxazepine antiproliferative activity antiviral activity
researchProduct